Twitter The 140 Moments That Made Twitter Matter Share Read Later prev134 of 141nextView AllThe #GameChangersWhen NASA’s TJ Creamer tweeted from spaceNov. 04, 2013 Hello Twitterverse! We r now LIVE tweeting from the International Space Station — the 1st live tweet from Space! :) More soon, send your ?s — TJ Creamer (@Astro_TJ) January 22, 2010 Enough said. Agree? Disagree? Tell us what you’d add to our list using hashtag #140moments Follow @TIME Next When @rsa sent the first @-reply Full List The #FailsWhen McDonald’s encouraged people to share their #McDStoriesWhen a Glee extra leaked plot detailsWhen Gilbert Gottfried made too-soon jokes after the Japan tsunamiWhen Entenmann’s had way too much fun with the Casey Anthony verdictWhen an e-retailer misinterpreted a trending topicWhen KitchenAid made a joke about Obama’s dead grandmotherWhen retailers tried to capitalize on Hurricane SandyWhen Chrysler dissed DetroitWhen Micky Arison vented about the NBA lockoutWhen The Onion insulted a 9-year-old actressWhen the NRA tweeted “Good Morning, Shooters” the day after the Aurora, Colo. rampageWhen these Olympians medaled in racismWhen @Sweden’s citizen takeover went horribly wrongWhen Kenneth Cole tried to use the Arab Spring to sell shoesWhen Anthony Weiner tweeted a picture of his weinerThe #FeudsWhen T. Boone Pickens schooled DrakeWhen Charmin put a comedian in his placeWhen the L.A. Kings burned the New Jersey DevilsWhen Trent Reznor digged at Chris CornellWhen the MySpace founder shot back at a random criticWhen Aimee Mann sparred with Ice-TWhen Don Lemon put Jonah Hill on blastWhen Cory Booker zinged a followerWhen Zayn from One Direction took on Max from The WantedWhen Brian Wilson swung back at John McCainWhen Donald Trump and a Modern Family staffer sparred about ChinaWhen Kanye West railed against Jimmy KimmelWhen Amanda Bynes went after Rihanna, Drake and the ObamasWhen Hope Solo beefed with Brandi ChastainWhen the Dallas Cowboys took a swipe at the NHLWhen AMC tussled with OreoWhen McDonald’s fought back against the Bloomberg soda banWhen President Obama responded to Clint Eastwood’s “empty chair” bitWhen Taco Bell burned Old SpiceThe #ScoopsWhen users posted photos from the Boston Marathon bombingWhen @jkrums posted a photo of the Hudson plane crashWhen @stefmara captured the Space Shuttle Endeavor launch from her plane windowWhen @judecallegari reportedly outed “Robert Galbraith” as a J.K. Rowling pen nameWhen the Sun Microsystems CEO announced his resignationWhen @MalikAlAbdeh “confirmed” Muammar Gaddafi’s deathWhen the president of Ecuador declared a state of emergencyWhen Clarence House announced the Royal EngagementWhen the president of Iran addressed freedom of informationWhen @AjaDiorNavy broke news of Whitney Houston’s deathWhen Sohaib Athar unknowingly live-tweeted the Bin Laden raidThe #StuntsWhen Nickelback addressed its haters directlyWhen Giraldo Rivera tweeted a shirtless selfieWhen Smart Car proved that bird poop could not total one of its vehiclesWhen Stephen Colbert renamed tweets “gurgles”When NASCAR’s Brad Keselowski live-tweeted the Daytona 500—while drivingWhen Jimmy Kimmel boosted the Emmys viewershipWhen James Cameron “tweeted” from the bottom of the oceanWhen Chipotle fake-hacked its own accountWhen Charlie Sheen started #winningWhen a BuzzFeed employee launched @horse_ebooksWhen Shaq meet his followers in personWhen Jennifer Egan tweeted an entire original short storyWhen a teenager faked her own kidnappingWhen a man spent more than $1,000 to put British Airways on blastWhen Samsung sent a man to the top of Mount Everest—to tweet from a Galaxy S2When Memorial Hermann Hospital live-tweeted an open-heart surgeryWhen @antitheistangie live-tweeted her abortionWhen Wendy’s raised $500,000 for foster childrenWhen Oreo scored the most talked-about ad of Super Bowl XLVII—for freeThe #BacktracksWhen the American Red Cross slyly acknowledged a wayward tweetWhen Sainsbury’s geeked outWhen Daniel Tosh quipped about his rape-joke apologyWhen Rupert Murdoch apologizedWhen John Mayer addressed his racist remarksWhen a Malaysian man posted 100 court-ordered apologiesWhen Ashton Kutcher took a leave of absenceWhen Kanye West humbled himselfThe #RantsWhen 50 Cent couldn’t believe he had to take out the trashWhen Lady Gaga addressed her hatersWhen Miley Cyrus threatened her dadWhen Family Feud slammed the Tea PartyWhen Evan Williams ripped an early Twitter haterWhen some Americans took issue with Miss America’s raceWhen Alec Baldwin got kicked off an American Airlines flight for playing Words With FriendsWhen Kevin Smith was told he was too fat to flyWhen a group of ex-employees put HMV on blastWhen Kanye West announced his new companyWhen T.J. Lang ripped the NFLThe #RavesWhen astronaut Chris Hadfield tweeted an adorable goodbye photoWhen Cory Booker complimented a stripperWhen Michael Dell championed entrepreneurshipWhen celebrities rallied around a terminally ill teenWhen Justin Bieber memorialized a fanWhen @richarddeitsch asked users to submit photos of the best moment in their livesWhen a U.S. congressman conceded to his opponent with a complimentWhen Chad Ochocino and John Boehner started a bromanceWhen Japanese users posted 143,199 tweets per second about Castle in the SkyWhen Bill Gates remembered Steve JobsWhen President Obama celebrated his reelectionThe #LOLzWhen Jaden Smith waxed philosophicalWhen @FakeAPStylebook launchedWhen Waffle House made a Drake jokeWhen @big_ben_clock tweeted its first BONGWhen Patrick Stewart posed in front of a Picard signWhen Tyrese thought “Pandora” was a personWhen the Nobel committee couldn’t reach certain winners via phoneWhen the cast of The West Wing reunitedWhen @ElBloombito launchedWhen Martha Stewart expected Apple to pick up her broken iPadWhen Sen. Chuck Grassley @-replied himselfWhen John McCain aligned himself with SnookiWhen the White House made a Mean Girls jokeWhen NASA broke legitimate news—with a sense of humorThe #DebutsWhen Prince tweetedWhen Conan O’Brien joinedWhen Warren Buffett joinedWhen Barack Obama tweetedWhen @kickbee tweeted from the wombWhen Justin Bieber joinedWhen Mark Zuckerberg joinedWhen Pope Benedict XVI tweetedWhen Oprah joinedWhen Jack Dorsey joinedThe #GameChangersWhen Greg Rewis proposed to Stephanie SullivanWhen @ShitMyDadSays became a TV showWhen thousands vowed to #StandWithWendyWhen Ashton Kutcher passed a million followersWhen @ComfortablySmug spread fake news about Hurricane SandyWhen @BPGlobalPR skewered BPWhen the world embraced Japan during the tsunamiWhen the White House welcomed Russian President Dmitry MedvedevWhen @persiankiwi started live-tweeting the 2009 Iran election protestsWhen the Syrian Electronic Army hacked the AP’s accountWhen Twitter bought VineWhen a tweet helped free @jamesbuck from an Egyptian jailWhen Israel announced an attack on GazaWhen Ann Curry helped convince the U.S. Air Force to allow a Doctors Without Borders flight to land in HaitiWhen the Library of Congress decided to archive every tweetWhen NASA’s TJ Creamer tweeted from spaceWhen @rsa sent the first @-replyWhen @chrismessina used the first hashtagWhen #OccupyWallStreet was bornWhen Comedy Central put a hashtag on live TVWhen Twitter announced its IPOWhen Twitter powered a revolution